Detection of Human papillomavirus and the role of p16INK4a in colorectal carcinomas.
Larisse Silva Dalla LiberaThalita de SiqueiraIgor Lopes Dos SantosJéssica Enocencio Porto RamosAmanda Xavier MilhomenRita de Cassia Gonçalves de AlencarSilvia Helena Rabelo SantosMegmar Aparecida Dos Santos CarneiroRosane Ribeiro Figueiredo AlvesVera Aparecida SaddiPublished in: PloS one (2020)
Based on these results, HPV is unlikely to be involved in colorectal carcinogenesis and p16INK4a expression is not a relevant marker of transcriptionally active HPV infection in CRC.