Randomised clinical trial: 48 weeks of treatment with tenofovir amibufenamide versus tenofovir disoproxil fumarate for patients with chronic hepatitis B.

Zhihong LiuQinglong JinYuexin ZhangGuozhong GongGuicheng WuLvfeng YaoXiaofeng WenZhiliang GaoYan HuangDaokun YangEn-Qiang ChenQing MaoShide LinJia ShangHuanyu GongLihua ZhongHuafa YinFengmei WangPeng HuLing XiaoChuan LiQiong WuChang'an SunJunqi Niu Jin-Lin Hounull null

Published in: Alimentary pharmacology & therapeutics (2021)

TMF was non-inferior to TDF in terms of anti-HBV efficacy and showed better bone and renal safety. (NCT03903796).

Keyphrases

clinical trial
hepatitis b virus
open label
double blind
study protocol
antiretroviral therapy
bone mineral density
liver failure
randomized controlled trial
placebo controlled
postmenopausal women
gestational age