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Targeting squalene epoxidase restores anti-PD-1 efficacy in metabolic dysfunction-associated steatohepatitis-induced hepatocellular carcinoma.

Jun WenXiang ZhangChi Chun WongYating ZhangYasi PanYunfei ZhouAlvin Ho-Kwan CheungYali LiuFenfen JiXing KangDabin LiuJun Yu
Published in: Gut (2024)
T cell function and augmenting immunosuppressive MDSCs. SQLE is a promising target in boosting anti-PD-1 immunotherapy for MASH-HCC.
Keyphrases
  • high glucose
  • diabetic rats
  • oxidative stress
  • drug induced
  • endothelial cells
  • stress induced