Serotonin receptor 1A promoter polymorphism, rs6295, modulates human anxiety levels via altering parasympathetic nervous activity.

J-H HuangH-A ChangW-H FangP-S HoY-P LiuF-J WanN-S TzengJ-F ShyuChuan-Chia Chang

Published in: Acta psychiatrica Scandinavica (2018)

These results are the first to show that HTR1A -1019C/G polymorphism influences anxiety levels by modulating parasympathetic tone, providing a neurophysiological insight into the role of HTR1A in human anxiety.

Keyphrases

endothelial cells
sleep quality
induced pluripotent stem cells
heart rate variability
pluripotent stem cells
dna methylation
gene expression
signaling pathway
transcription factor
blood pressure
heart rate