A Call for Caution in Use of Pertussis Vaccine Effectiveness Studies to Estimate Waning Immunity: A Canadian Immunization Research Network Study.
Natasha Sarah CrowcroftKevin L SchwartzRachel D SavageCynthia ChenCaitlin JohnsonYe LiAlex Marchand-AustinShelly BolotinShelley L DeeksFrances B JamiesonSteven J DrewsMargaret L RussellLawrence W SvensonKimberley SimmondsChristiaan H RigholtChristopher BellSalaheddin M MahmudJeffrey C KwongPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
The FMD adjusted better for healthcare-seeking behavior than the TND. Duration of protection from pertussis vaccines is unclear because estimates vary by study design. Caution should be exercised by experts, researchers, and decision makers when evaluating evidence on optimal timing of boosters.