Multi-Institutional Audit of FLASH and Conventional Dosimetry With a 3D Printed Anatomically Realistic Mouse Phantom.

M Ramish AshrafStavros MelemenidisKevin LiuVeljko GriljJeannette JansenBrett VelasquezLuke ConnellJoseph B SchulzClaude BailatAaron LibedRakesh ManjappaSuparna DuttLuis SotoBrianna LauAaron GarzaWilliam LarsenLawrie SkinnerAmy S YuMurat SurucuEdward E GravesPeter G MaximStephen F KryMarie-Catherine VozeninEmil SchülerBilly W Loo

Published in: International journal of radiation oncology, biology, physics (2024)

This study marks the first dosimetric audit for FLASH using a nonhomogeneous phantom, challenging conventional calibration practices reliant on homogeneous phantoms. The comparison protocol offers a framework for credentialing multi-institutional studies in FLASH preclinical research to enhance reproducibility of biologic findings.

Keyphrases

monte carlo
primary care
healthcare
radiation therapy
randomized controlled trial
rheumatoid arthritis
image quality
magnetic resonance
dual energy
computed tomography
magnetic resonance imaging
low cost