Serum insulin-like growth factor-I levels are associated with improved white matter recovery after traumatic brain injury.
Claire FeeneyDavid J SharpPeter J HellyerAmy E JollyJames H ColeGregory ScottDavid BaxterSagar JilkaEwan RossTimothy E HamPeter O JenkinsLucia M LiNikos GorgoraptisMark MidwinterAnthony P GoldstonePublished in: Annals of neurology (2017)
WM recovery and memory improvements after TBI were greater in patients with higher serum IGF-I at baseline. These findings suggest that the growth hormone/IGF-I system may be a potential therapeutic target following TBI. Ann Neurol 2017;82:30-43.