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Platelet-concentrated and platelet poor-plasma promote different pattern on immunohistochemical expression of TGF-β1, however they impairs the osteoneogensis in calvarial defects treated with autograft due suppression of osteocalcin.

Marco Antonio de Oliveira-FilhoMarcelo SouzaFernando Issamu TabushiLuís Eduardo AlmeidaFernanda Pirajá FigueiredoElora Sampaio LourencoAllan Fernando GiovaniniOsvaldo MalafaiaJurandir Marcondes Ribas-Filho
Published in: Acta cirurgica brasileira (2021)
PC and PPP were not effective when applied in association with ABG. Similarly, isolated use of PPP was not beneficial in optimizing the bone repair.
Keyphrases
  • bone regeneration
  • poor prognosis
  • transforming growth factor
  • bone mineral density
  • soft tissue
  • binding protein
  • epithelial mesenchymal transition
  • signaling pathway