A Multicenter Retrospective Study Evaluating Intravenous to Oral Antibiotic Stepdown for Uncomplicated Streptococcal Bacteremia.

Alison K LewMadison E SalamAlan E GrossSheila K WangErin McGuireNatasha N PettitJennifer PisanoCynthia T Nguyen

Published in: Open forum infectious diseases (2024)

Patients transitioned to PO antibiotics for uncomplicated streptococcal bacteremia had similar rates of clinical success compared to patients who received only IV therapy. With consideration of infectious source, severity of illness, and comorbidities, PO stepdown following initial IV antibiotics for uncomplicated streptococcal bacteremia in select patients is a reasonable approach that may result in decreased LOS and line-related complications.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
urinary tract infection
stem cells
mesenchymal stem cells
cross sectional
patient reported outcomes