Cell dynamics in human villous trophoblast.
John D AplinCarolyn J P JonesPublished in: Human reproduction update (2022)
The hypothesis requires experimental testing, moving research away from currently accepted methodology towards a new standard that includes representative cell and tissue sampling, assessment of cell cycle and differentiation parameters, and robust classification of cell subpopulations in villous trophoblast, with due attention to gestational age, maternal and fetal phenotype, disease and outcome.