Assessment of MMP-2/-9 expression by fluorescence endoscopy for evaluation of anastomotic healing in a murine model of anastomotic leakage.

Philipp-Alexander NeumannVanessa TwardyFelix BeckerChristiane GeyerKatrin SchwegmannAnnika MohrAndreas FaustPhilipp LenzEmile Rijcken

Published in: PloS one (2018)

During disturbed anastomotic healing increased expression of MMP-2/-9 was observed in the anastomotic tissue. Fluorescence endoscopy for detection of MMP-2/-9 during the healing process might be a promising tool for early identification of anastomotic leakage.

Keyphrases

rectal cancer
poor prognosis
single molecule
cell migration
binding protein
long non coding rna
small bowel
loop mediated isothermal amplification