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Clinical Outcomes of Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma: A Retrospective Analysis of 191 Patients from the NEJ023 Study.

Kazunari TateishiRyo KoTakehito ShukuyaYusuke OkumaSatoshi WatanabeShoichi KuyamaKyoko MuraseYoko TsukitaHironori AshinumaTaku NakagawaKazutsugu UematsuMika NakaoYoshiaki MoriKyoichi KairaAtsuto MouriTakao MiyabayashiHiroyuki SakashitaYoko MatsumotoTomoyuki TanigawaTomonobu KoizumiSatoshi MoritaKunihiko KobayashiToshihiro NukiwaKazuhisa Takahashinull null
Published in: The oncologist (2019)
Owing to the rarity of this tumor, there is limited information about second-line chemotherapy for patients with previously treated advanced thymic carcinoma. This is the largest data for those patients treated with second-line chemotherapy. This study suggests there is no significant difference in efficacy between monotherapy and multidrug chemotherapy for previously treated advanced thymic carcinoma. This result can support the adequacy to select monotherapy as treatment of those patients.
Keyphrases
  • locally advanced
  • newly diagnosed
  • combination therapy
  • ejection fraction
  • squamous cell carcinoma
  • randomized controlled trial
  • electronic health record
  • deep learning
  • data analysis
  • replacement therapy