Uncovering molecular mechanisms for amelanotic/hypopigmented primary cutaneous melanoma.
Richard A SturmDarren J SmitDavid L DuffyCatriona A McleanRichard A ScolyerGrant A McArthurAnthony T PapenfussMitchell S StarkHans Peter SoyerVictoria J MarPublished in: The British journal of dermatology (2024)
This study proposes that the likely molecular mechanism for development of amelanogenesis in AHM is carriage of an albinism/hypopigmentation allele followed by LOH of the corresponding gene in the tumour.