PD-L1 assessment in pediatric rhabdomyosarcoma: a pilot study.

Giulia BertoliniLuca BergamaschiAndrea FerrariSalvatore L RennePaola ColliniCecilia GardelliMarta BarisellaGiovanni CentonzeStefano ChiaravalliCinzia PaolinoMassimo MilioneMaura MassiminoMichela CasanovaPatrizia Gasparini

Published in: BMC cancer (2018)

Here we identify a peculiar pattern of PD-L1 expression in our RMS series with scanty positive-tumor cells detected by flow cytometry, and recurrent expression in the immune cells surrounding or infiltrating the tumor burden.

Keyphrases

flow cytometry
poor prognosis
binding protein
risk factors
young adults
childhood cancer