Interferon-Induced Transmembrane Protein 3 Expression Upregulation Is Involved in Progression of Hepatocellular Carcinoma.

Yuli HouShanshan WangMengdan GaoJing ChangJianping SunLing QinAng LiFudong LvJinli LouYonghong Zhang Yan Zhao

Published in: BioMed research international (2021)

Upregulation of IFITM3 plays a role in the development of HCC. Possibly through regulating HCC cell proliferation and migration, these effects are associated with the PI3K/AKT/mTOR signaling pathway. Upregulation of IFITM3 is also associated with the IFITM3 rs12252-CC genotype.

Keyphrases

signaling pathway
poor prognosis
cell proliferation
pi k akt
single cell
epithelial mesenchymal transition
induced apoptosis
high glucose
diabetic rats
dendritic cells
stem cells
oxidative stress