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Inferring the composition of a mixed culture of natural microbial isolates by deep sequencing.

Mark VoorhiesBastian JoehnkJessie UehlingKeith WalcottClaire DubinHeather L MeadChristina M HomerJohn N GalgianiBridget Marie BarkerRachel B BremAnita Sil
Published in: bioRxiv : the preprint server for biology (2024)
strains at environmental and host temperatures. We identify robustly growing and temperature-sensitive strains, confirm these inferences in validation pooled growth experiments, and successfully demonstrate their use in GWAS.
Keyphrases
  • escherichia coli
  • microbial community
  • single cell
  • human health
  • randomized controlled trial
  • climate change
  • genome wide association study