A nonrandomized trial of vitamin D supplementation for Barrett's esophagus.

Linda C CummingsPrashanthi N ThotaJoseph E WillisYanwen ChenGregory S CooperNancy FureyBeth BednarchikBronia M AlashkarJohn DumotAshley L FaulxStephen P FinkAdam M KresakBasel AbusneinehJill Barnholtz-SloanPatrick LeahyMartina L VeiglAmitabh ChakSanford D Markowitz

Published in: PloS one (2017)

BE subjects were vitamin D insufficient. Despite improved vitamin D status with supplementation, no significant alterations in gene expression profiles were noted. If vitamin D supplementation benefits BE, a longer duration or higher dose of supplementation may be needed.

Keyphrases

study protocol
clinical trial
phase iii
copy number
genome wide
phase ii
randomized controlled trial
dna methylation