Artificial intelligence for neurodegenerative experimental models.

Sarah J Marzi Brian M Schilder Alexi Nott Carlo Sala Frigerio Sandrine Willaime-Morawek Magda Bucholc Diane P Hanger Charlotte James Patrick A Lewis Ilianna Lourida Wendy Noble Francisco Rodriguez-Algarra Jalil-Ahmad SharifMaria TsalenchukLaura M Winchester Ümran YamanZhi Yaonull nullJanice M RansonDavid J Llewellyn

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)

There are increasing applications of AI in experimental medicine. We identified issues in reproducibility, cross-species translation, and data curation in the field. Our review highlights data resources and AI approaches as solutions. Multi-omics analysis with AI offers exciting future possibilities in drug discovery.

Keyphrases

artificial intelligence
big data
drug discovery
machine learning
deep learning
electronic health record
single cell
genetic diversity