Patrick A Lewis (Patrick Lewis)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 31

Top Venues

Cells

medRxiv : the preprint server for health sciences

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

NPJ Parkinson's disease

Royal Veterinary College

University College London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Royal Veterinary College Jan 01 2020

United Kingdom

Professor of Neuroscience :: Comparative Biomedical Sciences

University of Reading Oct 01 2013 - Dec 31 2019

United Kingdom

Associate Professor :: School of Pharmacy

UCL Institute of Neurology, University College London Oct 01 2007 - Oct 01 2013

United Kingdom

Senior research fellow :: Molecular neuroscience

National Institutes of Health Oct 01 2005 - Oct 01 2007

United States

Visiting Fellow :: National Institute on Aging

Education History

University College London Oct 01 2001 - Jun 01 2005

United Kingdom

PHD :: Institute of Neurology

University of Manchester Oct 01 1997 - Jun 30 2001

United Kingdom

BSC :: Biological Sciences

Publications

Noopur Bhore, Erin C Bogacki, Benjamin O'Callaghan, Helene Plun-Favreau, Patrick A Lewis, Susanne Herbst
Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 379 (1899) (2024)
Yibo Zhao, Matthew Bracher-Smith, Yuelin Li, Kirsten Harvey, Valentina Escott-Price, Patrick A Lewis, Claudia Manzoni
Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson's Disease. NPJ Parkinson's disease 10 (1) (2024)
Noopur Bhore, Erin C Bogacki, Benjamin O'Callaghan, Helene Plun-Favreau, Patrick A Lewis, Susanne Herbst
Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 379 (1899) (2024)
Francesca Magrinelli, Christelle Tesson, Plamena R Angelova, Ainara Salazar-Villacorta, Jose A Rodriguez, Annarita Scardamaglia, Brian Hon-Yin Chung, Matthew Jaconelli, Barbara Vona, Noemí Esteras, Anna Ka-Yee Kwong, Thomas Courtin, Reza Maroofian, Shahryar Alavi, Raja S Nirujogi, Mariasavina Severino, Patrick A Lewis, Stephanie Efthymiou, Benjamin J O'Callaghan, Rebecca Buchert, Linda Sofan, Pawel Lis, Chloé Pinon, Guido J Breedveld, Martin Man Chun Chui, David P Murphy, Vanessa Pitz, Mary B Makarious, Marlene Cassar, Bassem A Hassan, Sana Iftikhar, Clarissa Rocca, Peter Bauer, Michele Tinazzi, Marina Svetel, Bedia Samanci, Hasmet A Hanagasi, Basar Bilgiç, Jose A Obeso, Mónica M Kurtis, Guillaume Cogan, Ayse Nazli Basak, Güneş Kiziltan, Tuğçe Gül, Gül Yalçın Çakmaklı, Bülent Elibol, Nina Barisic, Earny Wei-Sen Ng, Sze-Shing Fan, Tova Hershkovitz, Karin Weiss, Javeria Raza Alvi, Tipu Sultan, Issam Azmi Alkhawaja, Tawfiq Froukh, Hadeel Abdollah E Alrukban, Christine Fauth, Ulrich A Schatz, Thomas Zöggeler, Michael Zech, Karen L Stals, Vinod C Varghese, Sonia Gandhi, Cornelis Blauwendraat, John A Hardy, Suzanne Lesage, Vincenzo Bonifati, Tobias B Haack, Aida Maria Bertoli-Avella, Robert Steinfeld, Dario R Alessi, Hermann Steller, Alexis Brice, Andrey Y Abramov, Kailash P Bhatia, Henry Houlden
PSMF1 variants cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality by disrupting mitochondrial pathways. medRxiv : the preprint server for health sciences (2024)
Francesca Magrinelli, Christelle Tesson, Plamena R Angelova, Ainara Salazar-Villacorta, Jose A Rodriguez, Annarita Scardamaglia, Brian Hon-Yin Chung, Matthew Jaconelli, Barbara Vona, Noemí Esteras, Anna Ka-Yee Kwong, Thomas Courtin, Reza Maroofian, Shahryar Alavi, Raja S Nirujogi, Mariasavina Severino, Patrick A Lewis, Stephanie Efthymiou, Benjamin J O'Callaghan, Rebecca Buchert, Linda Sofan, Pawel Lis, Chloé Pinon, Guido J Breedveld, Martin Man Chun Chui, David P Murphy, Vanessa Pitz, Mary B Makarious, Marlene Cassar, Bassem A Hassan, Sana Iftikhar, Clarissa Rocca, Peter Bauer, Michele Tinazzi, Marina Svetel, Bedia Samanci, Hasmet A Hanagasi, Basar Bilgiç, Jose A Obeso, Mónica M Kurtis, Guillaume Cogan, Ayse Nazli Basak, Güneş Kiziltan, Tuğçe Gül, Gül Yalçın Çakmaklı, Bülent Elibol, Nina Barisic, Earny Wei-Sen Ng, Sze-Shing Fan, Tova Hershkovitz, Karin Weiss, Javeria Raza Alvi, Tipu Sultan, Issam Azmi Alkhawaja, Tawfiq Froukh, Hadeel Abdollah E Alrukban, Christine Fauth, Ulrich A Schatz, Thomas Zöggeler, Michael Zech, Karen L Stals, Vinod C Varghese, Sonia Gandhi, Cornelis Blauwendraat, John A Hardy, Suzanne Lesage, Vincenzo Bonifati, Tobias B Haack, Aida Maria Bertoli-Avella, Robert Steinfeld, Dario R Alessi, Hermann Steller, Alexis Brice, Andrey Y Abramov, Kailash P Bhatia, Henry Houlden
PSMF1 variants cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality by disrupting mitochondrial pathways. medRxiv : the preprint server for health sciences (2024)
Noopur Bhore, Erin C Bogacki, Benjamin O'Callaghan, Helene Plun-Favreau, Patrick A Lewis, Susanne Herbst
Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 379 (1899) (2024)
Francesca Magrinelli, Christelle Tesson, Plamena R Angelova, Ainara Salazar-Villacorta, Jose A Rodriguez, Annarita Scardamaglia, Brian Hon-Yin Chung, Matthew Jaconelli, Barbara Vona, Noemí Esteras, Anna Ka-Yee Kwong, Thomas Courtin, Reza Maroofian, Shahryar Alavi, Raja S Nirujogi, Mariasavina Severino, Patrick A Lewis, Stephanie Efthymiou, Benjamin J O'Callaghan, Rebecca Buchert, Linda Sofan, Pawel Lis, Chloé Pinon, Guido J Breedveld, Martin Man Chun Chui, David P Murphy, Vanessa Pitz, Mary B Makarious, Marlene Cassar, Bassem A Hassan, Sana Iftikhar, Clarissa Rocca, Peter Bauer, Michele Tinazzi, Marina Svetel, Bedia Samanci, Hasmet A Hanagasi, Basar Bilgiç, Jose A Obeso, Mónica M Kurtis, Guillaume Cogan, Ayse Nazli Basak, Güneş Kiziltan, Tuğçe Gül, Gül Yalçın Çakmaklı, Bülent Elibol, Nina Barisic, Earny Wei-Sen Ng, Sze-Shing Fan, Tova Hershkovitz, Karin Weiss, Javeria Raza Alvi, Tipu Sultan, Issam Azmi Alkhawaja, Tawfiq Froukh, Hadeel Abdollah E Alrukban, Christine Fauth, Ulrich A Schatz, Thomas Zöggeler, Michael Zech, Karen L Stals, Vinod C Varghese, Sonia Gandhi, Cornelis Blauwendraat, John A Hardy, Suzanne Lesage, Vincenzo Bonifati, Tobias B Haack, Aida Maria Bertoli-Avella, Robert Steinfeld, Dario R Alessi, Hermann Steller, Alexis Brice, Andrey Y Abramov, Kailash P Bhatia, Henry Houlden
PSMF1 variants cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality by disrupting mitochondrial pathways. medRxiv : the preprint server for health sciences (2024)
Yibo Zhao, Matthew Bracher-Smith, Yuelin Li, Kirsten Harvey, Valentina Escott-Price, Patrick A Lewis, Claudia Manzoni
Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson's Disease. NPJ Parkinson's disease 10 (1) (2024)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Katie Kelly, Patrick A Lewis, Hélène Plun-Favreau, Claudia Manzoni
Protein network analysis links the NSL complex to Parkinson's disease via mitochondrial and nuclear biology. Molecular omics (2023)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Christiane Zhu, Susanne Herbst, Patrick A Lewis
Leucine-rich repeat kinase 2 at a glance. Journal of cell science 136 (17) (2023)
Sarah J Marzi, Brian M Schilder, Alexi Nott, Carlo Sala Frigerio, Sandrine Willaime-Morawek, Magda Bucholc, Diane P Hanger, Charlotte James, Patrick A Lewis, Ilianna Lourida, Wendy Noble, Francisco Rodriguez-Algarra, Jalil-Ahmad Sharif, Maria Tsalenchuk, Laura M Winchester, Ümran Yaman, Zhi Yao, null null, Janice M Ranson, David J Llewellyn
Artificial intelligence for neurodegenerative experimental models. Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A Lewis, Jennifer M Pocock, Mark R Cookson, Rina Bandopadhyay
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells 13 (1) (2023)
Clara Ruz, José Luis Alcantud, Francisco Vives, Francisco Arrebola, John Hardy, Patrick A Lewis, Claudia Manzoni, Raquel Duran
Seventy-Two-Hour LRRK2 Kinase Activity Inhibition Increases Lysosomal GBA Expression in H4, a Human Neuroglioma Cell Line. International journal of molecular sciences 23 (13) (2022)
Jillian H Kluss, Patrick A Lewis, Greggio Elisa
Leucine-rich repeat kinase 2 (LRRK2): an update on the potential therapeutic target for Parkinson's disease. Expert opinion on therapeutic targets 26 (6) (2022)
Rachael J Chandler, Susanna Cogo, Patrick A Lewis, Eva Kevei
Modelling the functional genomics of Parkinson's disease in Caenorhabditis elegans: LRRK2 and beyond. Bioscience reports 41 (9) (2022)
Susanne Herbst, Patrick A Lewis, Huw R Morris
The emerging role of LRRK2 in tauopathies. Clinical science (London, England : 1979) 136 (13) (2022)
Jillian H Kluss, Alexandra Beilina, Chad D Williamson, Patrick A Lewis, Mark R Cookson, Luis Bonet-Ponce
Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 + lysosomes. Proceedings of the National Academy of Sciences of the United States of America 119 (43) (2022)
Patrick A Lewis
Vesicular dysfunction and pathways to neurodegeneration. Essays in biochemistry 65 (7) (2022)
Patrick A Lewis
A step forward for LRRK2 inhibitors in Parkinson's disease. Science translational medicine 14 (648) (2022)
Susanne Herbst, Patrick A Lewis
From structure to ætiology: a new window on the biology of leucine-rich repeat kinase 2 and Parkinson's disease. The Biochemical journal 478 (14) (2021)
Craig Blackstone, Fiona Elwood, Helene Plun-Favreau, Patrick A Lewis
Vesicle trafficking and pathways to neurodegeneration. Molecular neurodegeneration 16 (1) (2021)
Patrick A Lewis
Leucine rich repeat kinase 2: a paradigm for pleiotropy. The Journal of physiology 597 (14) (2019)
Luke W Bonham, Natasha Z R Steele, Celeste M Karch, Iris J Broce, Ethan G Geier, Natalie L Wen, Parastoo Momeni, John Hardy, Zachary A Miller, Maria Luisa Gorno-Tempini, Christopher P Hess, Patrick A Lewis, Bruce L Miller, William W Seeley, Claudia Manzoni, Rahul S Desikan, Sergio E Baranzini, Raffaele Ferrari, Jennifer S Yokoyama, null null
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia. Scientific reports 9 (1) (2019)
Patrick A Lewis
Mutations in LRRK2 amplify cell-to-cell protein aggregate propagation: a hypothesis. Acta neuropathologica 135 (6) (2018)
Alastair J Noyce, Demis A Kia, Gibran Hemani, Aude Nicolas, T Ryan Price, Eduardo De Pablo-Fernandez, Philip C Haycock, Patrick A Lewis, Thomas Foltynie, George Davey Smith, null null, Anette Schrag, Andrew J Lees, John Hardy, Andrew Singleton, Mike A Nalls, Neil Pearce, Deborah A Lawlor, Nicholas W Wood
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. PLoS medicine 14 (6) (2017)

Patrick A Lewis.css-eqlu8i{font-size:small;padding-left:4px;} (Patrick Lewis)

Publication Activity (10 Years)

Top Topics

Top Venues

Patrick A Lewis (Patrick Lewis)