Analysis of clinical and methodological characteristics of early COVID-19 treatment clinical trials: so much work, so many lost opportunities.
Beatrice MainoliTiago MachadoGonçalo S DuarteLuísa PradaNilza GonçalvesJoaquim J FerreiraJoão N CostaPublished in: BMC medical research methodology (2021)
Our results raise concerns about the success of the initial global research effort on COVID-19 treatment. The clinical and methodological characteristics of early COVID-19 treatment trials limit their capability to produce clear answers to critical questions in the shortest possible time.