Patterns of patient and healthcare provider viewpoints regarding participation in HIV cure-related clinical trials. Findings from a multicentre French survey using Q methodology (ANRS-APSEC).
Christel ProtièreBruno SpireMarion MoraIsabelle Poizot-MartinMarie PréauMarjolaine DoumerguePhilippe MorlatDavid ZucmanCécile GoujardFrançois RaffiOlivier LambotteMarie Suzan-MontiPublished in: PloS one (2017)
HIV cure research clinical trials (HCRCT) constitute a risky yet unavoidable step towards the goal of finding a cure. To improve future HCRCT and informed consent designs, based on PLWH and HHP preferences and expectations, we need greater knowledge about how these populations perceive the risks and the benefits of HCRCT. Our results confirmed the importance of careful, studied HCRCT design, management and communication, to ensure PLWH and HHP acceptability and convergence of their expectations.
Keyphrases
- clinical trial
- healthcare
- antiretroviral therapy
- hiv positive
- hiv testing
- hiv infected
- human immunodeficiency virus
- hiv aids
- hepatitis c virus
- men who have sex with men
- phase ii
- primary care
- cross sectional
- double blind
- physical activity
- case report
- open label
- current status
- human health
- climate change
- health insurance
- decision making
- solid state