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Recommendations for the responsible use and communication of race and ethnicity in neuroimaging research.

Carlos Cardenas-IniguezMarybel Robledo Gonzalez
Published in: Nature neuroscience (2024)
The growing availability of large-population human biomedical datasets provides researchers with unique opportunities to conduct rigorous and impactful studies on brain and behavioral development, allowing for a more comprehensive understanding of neurodevelopment in diverse populations. However, the patterns observed in these datasets are more likely to be influenced by upstream structural inequities (that is, structural racism), which can lead to health disparities based on race, ethnicity and social class. This paper addresses the need for guidance and self-reflection in biomedical research on conceptualizing, contextualizing and communicating issues related to race and ethnicity. We provide recommendations as a starting point for researchers to rethink race and ethnicity choices in study design, model specification, statistical analysis and communication of results, implement practices to avoid the further stigmatization of historically minoritized groups, and engage in research practices that counteract existing harmful biases.
Keyphrases
  • healthcare
  • primary care
  • endothelial cells
  • public health
  • clinical practice
  • rna seq
  • multiple sclerosis
  • risk assessment
  • pluripotent stem cells
  • single cell
  • brain injury
  • health insurance
  • social media
  • genetic diversity