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Longitudinal egg-specific regulatory T- and B-cell development: Insights from primary prevention clinical trials examining the timing of egg introduction.

Catherine L LaiDianne E CampbellDebra J PalmerMaria MakridesBrigitte Santner-NananMichael GoldJohn Wei-Liang TanCarol ValerioRalph NananSusan L PrescottPeter S Hsu
Published in: Allergy (2020)
Early egg introduction and clinical tolerance to egg were associated with expansion of ovalbumin-specific T and B regulatory cells, which may be an important developmental process for tolerance acquisition to food allergens.
Keyphrases
  • clinical trial
  • induced apoptosis
  • cell cycle arrest
  • randomized controlled trial
  • risk assessment
  • oxidative stress
  • signaling pathway
  • endoplasmic reticulum stress
  • human health
  • climate change
  • study protocol