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Treatment outcome of IDH1/2 wildtype CNS WHO grade 4 glioma histologically diagnosed as WHO grade II or III astrocytomas.

Naureen KericHarald KrenzlinDarius KalasauskasChristian F FreyschlagOliver SchnellMartin MischChristian von der BrelieJens GemptAleksandrs KrigersArthur WagnerFelipa LangeDorothee MielkeClemens SommerMarc A BrockmannBernhard MeyerVeit RohdePeter VajkoczyJürgen BeckClaudius ThoméFlorian Ringel
Published in: Journal of neuro-oncology (2024)
WHO grade 2 and 3 IDH1/2 wt astrocytomas, treated according to the same treatment protocols, have a similar OS. Age, extent of resection, and strong EGFR expression were the most important treatment related prognostic factors.
Keyphrases
  • prognostic factors
  • low grade
  • poor prognosis
  • blood brain barrier
  • long non coding rna
  • high grade
  • newly diagnosed