Disentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways.
Luiza Kvitko AxelrudMauricio Scopel HoffmannDaniel E VosbergMarcos Leite SantoroPedro Mario PanAry GadelhaSintia Nogueira BelangeroEurípedes Constantino MiguelJean ShinAnita ThaparJordan W SmollerZdenka PausovaLuis Augusto RohdeMatthew C KellerTomáš PausGiovanni Abrahão SalumPublished in: Journal of child psychology and psychiatry, and allied disciplines (2022)
Our findings indicate that parental genetics influences offspring cognition and educational attainment by genetic and phenotypic pathways, suggesting the expression of parental phenotypes partially explain the association between parental genetic risk and offspring outcomes. Multiple mediations might represent an effective approach to disentangle distinct pathways for intergenerational transmission of behavioral traits.