Nourin-Dependent miR-137 and miR-106b: Novel Early Inflammatory Diagnostic Biomarkers for Unstable Angina Patients.
Salwa A ElgebalyRobert H ChristensonHossam KandilNashwa El-KhazragyLaila RashedBeshoy YacoubHeba EldeebMahmoud AliRoshanak SharafiehUlrike KluehDonald L KreutzerPublished in: Biomolecules (2021)
Nourin-dependent gene expression of miR-137 and miR-106b-5p are novel blood-based biomarkers that can diagnose UA and STEMI patients at presentation and stratify severity of myocardial ischemia, with higher expression in STEMI compared to UA. Early diagnosis of suspected UA patients using the novel Nourin biomarkers is key for initiating guideline-based therapy that improves patients' health outcomes.
Keyphrases
- end stage renal disease
- gene expression
- ejection fraction
- newly diagnosed
- chronic kidney disease
- cell proliferation
- prognostic factors
- long non coding rna
- poor prognosis
- percutaneous coronary intervention
- heart failure
- oxidative stress
- stem cells
- acute coronary syndrome
- coronary artery
- st elevation myocardial infarction
- bone marrow
- pulmonary embolism
- long noncoding rna
- patient reported
- cell therapy