International multicenter examination of MOG antibody assays.
Markus ReindlKathrin SchandaMark WoodhallFiona TeaSudarshini RamanathanJessica SagenJames P FryerJohn MillsBianca TeegenSwantje MindorfNora RitterUlrike KrummreiWinfried StöckerJuliane EggertEoin P FlanaganMelanie RambergerHarald HegenKevin RostasyThomas BergerMaria Isabel LeiteJacqueline PalaceSarosh R IraniRussell C DaleChristian ProbstMonika ProbstFabienne BrilotSean J PittockPatrick J WatersPublished in: Neurology(R) neuroimmunology & neuroinflammation (2020)
Live MOG-IgG CBAs showed excellent agreement for high positive and negative samples at 3 international testing centers. Low positive samples were more frequently discordant than in a similar comparison of aquaporin-4 antibody assays. Further research is needed to improve international standardization for clinical care.