Predictive Factors for RAI-Refractory Disease and Short Overall Survival in PDTC.
David KerstingRobert SeifertLukas KesslerKen HerrmannSarah TheurerTim BrandenburgHenning DralleFrank WeberLale UmutluDagmar Führer-SakelRainer GörgesChristoph RischplerManuel WeberPublished in: Cancers (2021)
PDTC patients, especially those with additional risk factors, should be assessed for RAI-R disease at initial diagnosis and in the course of disease, allowing for early implementation of multimodal treatment. Primary tumor size >40 mm, ETE, and age >55 are significant risk factors for RAI-R disease. High MTV/TLG is a significant risk factor for premature death and can help identify patients requiring intervention.