Cumulative inflammatory burden and obesity as determinants of insulin resistance in patients with established rheumatoid arthritis: cross-sectional study.

Sara Manrique-ArijaNatalia Mena VázquezInmaculada UreñaJosé RiojaPedro ValdivielsoLeovigildo Ginel-MendozaSalomé Abad-SánchezFrancisco G Jiménez-NúñezBegoña Oliver-MartosAntonio Fernandez-Nebro

Published in: BMJ open (2021)

In patients with well-controlled, established RA, IR is associated mainly with poorer control of inflammation from diagnosis and with obesity, specifically total fat mass.

Keyphrases

rheumatoid arthritis
insulin resistance
metabolic syndrome
weight loss
oxidative stress
high fat diet induced
type diabetes
weight gain
disease activity
adipose tissue
interstitial lung disease
body mass index
skeletal muscle
risk factors
systemic lupus erythematosus
fatty acid
systemic sclerosis