A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.

David Christopher CurrowGareth John WattsMiriam JohnsonChristine F McDonaldJohn O MinersAndrew A SomogyiLinda DenehyNicola McCaffreyDanny J EckertPhilip McCloudSandra LouwLawrence LamAine GreeneBelinda FazekasKatherine C ClarkKwun FongMeera R AgarRohit JoshiSharon KilbreathDiana FerreiraMagnus Ekströmnull null

Published in: BMJ open (2017)

NCT02720822; Pre-results.

Keyphrases

study protocol
placebo controlled
phase iii
double blind
low dose
open label
randomized controlled trial
clinical trial
phase ii
phase ii study
high dose
drug induced
squamous cell carcinoma