The global prevalence of type-2 diabetes mellitus (T2DM) has caused harm to human health and economies. Cardiovascular disease is one main cause of T2DM mortality. Increased prevalence of diabetes and associated heart failure (HF) is common in older populations, so accurately evaluating heart-related injury and T2DM risk factors and conducting early intervention are important. Quantitative cardiovascular system imaging assessments, including functional imaging during cardiovascular disease treatment, are also important. The left-ventricular ejection fraction (LVEF) has been traditionally used to monitor cardiac function; it is often preserved or increased in early T2DM, but subclinical heart deformation and dysfunction can occur. Myocardial strains are sensitive to global and regional heart dysfunction in subclinical T2DM. Cardiac magnetic resonance feature-tracking technology (CMR-FT) can visualize and quantify strain and identify subclinical myocardial injury for early management, especially with preserved LVEF. Meanwhile, CMR-FT can be used to evaluate the multiple cardiac chambers involvement mediated by T2DM and the coexistence of complications. This review discusses CMR-FT principles, clinical applications, and research progress in the evaluation of myocardial strain in T2DM.
Keyphrases
- left ventricular
- heart failure
- risk factors
- cardiovascular disease
- magnetic resonance
- glycemic control
- aortic stenosis
- ejection fraction
- type diabetes
- human health
- high resolution
- acute myocardial infarction
- cardiac resynchronization therapy
- hypertrophic cardiomyopathy
- left atrial
- mitral valve
- risk assessment
- atrial fibrillation
- machine learning
- escherichia coli
- randomized controlled trial
- physical activity
- adipose tissue
- coronary artery disease
- deep learning
- skeletal muscle
- transcatheter aortic valve replacement
- aortic valve
- weight loss
- fluorescence imaging