MS-Based Analytical Techniques: Advances in Spray-Based Methods and EI-LC-MS Applications.
Federica BianchiNicolò RiboniVeronica TermopoliLucía MéndezIsabel MedinaLeopold L IlagAchille CappielloMaria CareriPublished in: Journal of analytical methods in chemistry (2018)
Mass spectrometry is the most powerful technique for the detection and identification of organic compounds. It can provide molecular weight information and a wealth of structural details that give a unique fingerprint for each analyte. Due to these characteristics, mass spectrometry-based analytical methods are showing an increasing interest in the scientific community, especially in food safety, environmental, and forensic investigation areas where the simultaneous detection of targeted and nontargeted compounds represents a key factor. In addition, safety risks can be identified at the early stage through online and real-time analytical methodologies. In this context, several efforts have been made to achieve analytical instrumentation able to perform real-time analysis in the native environment of samples and to generate highly informative spectra. This review article provides a survey of some instrumental innovations and their applications with particular attention to spray-based MS methods and food analysis issues. The survey will attempt to cover the state of the art from 2012 up to 2017.
Keyphrases
- mass spectrometry
- liquid chromatography
- high resolution mass spectrometry
- early stage
- human health
- tandem mass spectrometry
- multiple sclerosis
- gas chromatography
- high resolution
- capillary electrophoresis
- high performance liquid chromatography
- ms ms
- healthcare
- health information
- social media
- risk assessment
- squamous cell carcinoma
- loop mediated isothermal amplification
- radiation therapy
- quality improvement
- cancer therapy
- cross sectional
- lymph node