Impact of prone positioning on patients with COVID-19 and ARDS on invasive mechanical ventilation: a multicenter cohort study.
Marieta C A CunhaJociane SchardongNatiele Camponogara RighiAdriana Cláudia LunardiGuadalupe Nery de Sant'AnnaLarissa Padrão IsenseeRafaella Fagundes XavierKaciane Roberta BrambattiJosé Eduardo PompeuFabiano FrâncioLuiza Martins FariaRozana Astolfi CardosoAntônio Marcos Vargas da SilvaCamila de Christo DornelesRoberta Weber WerleJuliana Carvalho FerreiraRodrigo Della Méa PlentzCelso Ricardo Fernandes de CarvalhoPublished in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2022)
Our results show that most patients in our sample had a positive oxygenation response after the first prone positioning session. However, the mortality rate was high, probably due to the health status and the number of comorbidities of the patients, as well as the severity of their disease. Our results also suggest that SAPS III and the initial PaO2/FIO2 predict the oxygenation response; in addition, age, time to first prone positioning, number of sessions, pulmonary impairment, and immunosuppression can predict mortality.
Keyphrases
- end stage renal disease
- mechanical ventilation
- chronic kidney disease
- ejection fraction
- newly diagnosed
- acute respiratory distress syndrome
- peritoneal dialysis
- intensive care unit
- prognostic factors
- cardiovascular events
- type diabetes
- cardiovascular disease
- pulmonary hypertension
- cross sectional
- extracorporeal membrane oxygenation
- blood flow
- high intensity