Sonothrombolysis in Patients With Acute Ischemic Stroke With Large Vessel Occlusion: An Individual Patient Data Meta-Analysis.
Georgios K TsivgoulisAristeidis H KatsanosJürgen EggersVincent LarrueLars ThomassenJames C GrottaGeorgios SeitidisPeter Dieter SchellingerDimitris MavridisAndrew DemchukVojtech NovotnyCarlos A MolinaAreti Angeliki VeronikiMartin KöhrmannLauri SoinneAndrej Netland KhanevskiAndrew D BarretoMaher SaqqurTheodora PsaltopoulouKeith W MuirJochen B FiebachTravis RothlisbergerThomas A KentPitchaiah MandavaAnne W AlexandrovAndrei V AlexandrovPublished in: Stroke (2021)
Sonothrombolysis was associated with a nearly 2-fold increase in the odds of complete recanalization compared with intravenous thrombolysis alone in patients with AIS with large vessel occlusions. Further study of the safety and efficacy of sonothrombolysis is warranted.