RHCE diversity among Brazilian patients with sickle cell disease (SCD) and selected groups of blood donors.

Carine Prisco Arnoni Tatiane Aparecida de Paula Vendrame Janaína Guilhem Muniz Afonso Cortez Flavia Roche Moreira Latini Lilian Castilho

Published in: Transfusion (2021)

This study showed that even in an admixed population the selection of SDB donors is the best choice of matching for transfusion support in patients with SCD. For specific RHCE alleles, selection of donors with weak D expression could be a good option.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
poor prognosis
chronic kidney disease
prognostic factors
cardiac surgery
peritoneal dialysis
kidney transplantation
acute kidney injury
patient reported outcomes
binding protein
sickle cell disease
decision making
patient reported