Ambient Pollution-related Reprogramming of the Human Small Airway Epithelial Transcriptome.

Sarah L O'BeirneSushila A ShenoyJacqueline SalitYael Strulovici-BarelRobert J KanerSudha VisvanathanJay S FineJason G MezeyRonald G Crystal

Published in: American journal of respiratory and critical care medicine (2019)

PM2.5 exposure contributes to significant dysregulation of the SAE transcriptome of smokers, linking pollution and airway epithelial biology in the risk of development of respiratory disease in susceptible individuals.

Keyphrases

particulate matter
air pollution
heavy metals
rna seq
single cell
endothelial cells
genome wide
gene expression
risk assessment
health risk assessment
induced pluripotent stem cells
pluripotent stem cells
human health