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Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs.
Feng Sun
Ke Wu
Zhixian Yao
Xingyu Mu
Zhong Zheng
Menghao Sun
Yong Wang
Zhihong Liu
Yiyong Zhu
Published in:
OncoTargets and therapy (2020)
Taken together, our results show that PVT1 acts as an inducer of PCa metastasis via targeting miRNAs, thereby promoting NOP2. This axis may have diagnostic and therapeutic potential for advanced PCa.
Keyphrases
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long noncoding rna
prostate cancer
cancer therapy
poor prognosis
radical prostatectomy
drug delivery
binding protein