Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study.

Lisanne J BalkDanko CoricBenjamin KnierHanna G ZimmermannRaed BehbehaniRaed AlroughaniElena H Martinez-LapiscinaAlexander Ulrich BrandtBernardo Sánchez-DalmauÁngela Vidal-JordanaPhilipp AlbrechtValeria KoskaJoachim HavlaMarco PisaRachel C NolanLetizia LeocaniFriedemann PaulOrhan AktasXavier MontalbanLaura J BalcerPablo VillosladaOlivier OutteryckThomas KornAxel Petzoldnull null

Published in: Multiple sclerosis journal - experimental, translational and clinical (2019)

Our data demonstrate that an increase in INL volume is associated with MSON and the occurrence of clinical relapses. Therefore, INL volume changes may be useful as an outcome marker for inflammatory disease activity in MSON and MS treatment trials.

Keyphrases

disease activity
rheumatoid arthritis
systemic lupus erythematosus
multiple sclerosis
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
optical coherence tomography
oxidative stress
diabetic retinopathy
risk assessment
electronic health record
ms ms
white matter
big data