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Genetics of gallstone disease.

Charlotte RebholzMarcin KrawczykFrank Lammert
Published in: European journal of clinical investigation (2018)
Gallstone disease represents a multifactorial condition and previous studies have identified the major genetic contributors to gallstone formation. The increasing knowledge about the pathomechanisms of hepatobiliary metabolism and GD as well as the identification of additional risk factors might help to overcome the current invasive therapy by specific lifestyle intervention and precise molecular treatment.
Keyphrases
  • risk factors
  • randomized controlled trial
  • healthcare
  • metabolic syndrome
  • cardiovascular disease
  • weight loss
  • genome wide
  • stem cells
  • mesenchymal stem cells
  • dna methylation
  • single molecule
  • combination therapy