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Fluid boluses and infusions in the early phase of resuscitation from septic shock and sepsis-induced hypotension: a retrospective report and outcome analysis from a tertiary hospital.

Antonio MessinaMarco AlbiniNicolò SamuelliAndrea BrunatiElena CostantiniGiulia LionettiMarta LubianMassimiliano GrecoGuia Margherita MatronolaFabio PiccirilloDaniel De BackerJean Louis TeboulMaurizio Cecconi
Published in: Annals of intensive care (2024)
This retrospective analysis of fluids given over the early phases of septic shock and sepsis-induced hypotension showed that the overall volume given by boluses ranges from about 25% on Day 1 to about 5% on Day 4 from ICU admission. Our data confirms that a positive fluid balance over the first 4 days of ICU is associated with mortality.
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