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Ceftazidime-avibactam and aztreonam combination for Carbapenem-resistant Enterobacterales bloodstream infections with presumed Metallo-β-lactamase production: a systematic review and meta-analysis.

Nitin GuptaCarl BoodmanParikshit PrayagAbi ManeshTirlangi Praveen Kumar
Published in: Expert review of anti-infective therapy (2024)
The meta-analysis from studies with a high risk of bias shows that AA is associated with lesser 30-day mortality when compared to polymyxins in patients with MBL-producing CRE BSI. Registration with PROSPERO- CRD42023433608.
Keyphrases
  • gram negative
  • multidrug resistant
  • case control
  • systematic review
  • klebsiella pneumoniae
  • meta analyses
  • cardiovascular events
  • escherichia coli
  • randomized controlled trial
  • type diabetes
  • coronary artery disease