The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial.

Pär Ingemar JohanssonMorten BestlePeter Søe-JensenKlaus Tjelle KristiansenJakob StensballeNiels Erikstrup ClausenAnders Perner

Published in: Trials (2020)

Trial registration at clinicaltrialregisters.eu; EudraCT no. 2020-001296-33 on 3 April 2020 and at ClinicalTrials.gov Identifier: NCT04420741 on 9 June 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1).In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.

Keyphrases

randomized controlled trial
phase iii
intensive care unit
clinical trial
low dose
acute respiratory distress syndrome
phase ii
double blind
extracorporeal membrane oxygenation