Prostate Artery Embolization: Challenges, Tips, Tricks, and Perspectives.
Benjamin MoulinMassimiliano Di PrimioOlivier VignauxJean Luc SarrazinGeorgios AngelopoulosAntoine HakimePublished in: Journal of personalized medicine (2022)
Prostatic artery embolization (PAE) consists of blocking the arteries supplying the prostate to treat benign prostate hypertrophia (BPH). Its effectiveness on both urinary symptoms and flowmetric parameters has now been amply demonstrated by around a hundred studies, including several randomized trials. The main advantage of this procedure is the very low rate of urinary and sexual sequelae, including ejaculatory, with an excellent tolerance profile. The arterial anatomy is a key element for the realization of PAE. Its knowledge makes it possible to anticipate obstacles and prevent potential complications related to nontarget embolization. Nontarget embolization can occur with a small intraprostatic shunt or reflux and has no consequences except some local inflammation symptoms that resolve in a couple of days. Nevertheless, some situations with large arterial shunts arising from the prostatic artery must be recognized (accessory rectal, bladder, or pudendal branches), and must imperatively be protected before embolization, at the risk of exposing oneself to otherwise ischemic complications that are more severe, such as bladder necrosis and skin or mucosal necrosis. This article offers a step-by-step review of the various anatomical and technical key points to ensure technical and clinical success, while avoiding the occurrence of adverse events.
Keyphrases
- benign prostatic hyperplasia
- lower urinary tract symptoms
- prostate cancer
- radical prostatectomy
- spinal cord injury
- randomized controlled trial
- oxidative stress
- healthcare
- systematic review
- risk factors
- risk assessment
- minimally invasive
- early onset
- physical activity
- pulmonary artery
- coronary artery
- ischemia reperfusion injury
- urinary tract