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Expression of NANOG and Its Regulation in Oral Squamous Cell Carcinoma.

Gašper GrubelnikEmanuela BoštjančičAleš GrošeljNina Zidar
Published in: BioMed research international (2020)
Our findings confirm the diagnostic significance of NANOG in OSCC and provide information on NANOG expression patterns on both mRNA and protein levels. They also suggest that protein regulators and microRNAs might play a crucial role, whereas methylation of its promoter and copy number variation probably have a minor role in the regulation of NANOG expression in OSCC.
Keyphrases
  • poor prognosis
  • copy number
  • binding protein
  • dna methylation
  • mitochondrial dna
  • cancer stem cells
  • genome wide
  • transcription factor
  • long non coding rna
  • healthcare
  • protein protein
  • embryonic stem cells
  • amino acid