The mediating effect of DNA methylation in the association between maternal sleep during pregnancy and offspring adiposity status: a prospective cohort study.
Min MengYanrui JiangJianfei LinJun ZhangGuanghai WangQi ZhuQingmin LinFan JiangPublished in: Clinical epigenetics (2022)
Maternal later sleep timing in late pregnancy was associated with higher childhood adiposity in the offspring. Cord blood DNA methylation may play a mediation role in that relationship.
Keyphrases
- dna methylation
- cord blood
- pregnancy outcomes
- high fat diet
- birth weight
- insulin resistance
- weight gain
- genome wide
- gene expression
- sleep quality
- physical activity
- pregnant women
- preterm birth
- adipose tissue
- copy number
- gestational age
- social support
- type diabetes
- skeletal muscle
- depressive symptoms
- childhood cancer
- weight loss