Drug Repurposing in Crohn's Disease Using Danish Real-World Data.
Saeed ShakibfarKristine Højgaard AllinTine JessMaria Antonietta BarbieriVera BattiniEva SimoncicJulien KirchgesnerTrond UlvenMaurizio SessaPublished in: Pragmatic and observational research (2024)
This study focuses on repurposing existing drugs to prevent surgery related to intestinal fibrosis in CD patients, using Danish EHRs and advanced statistical methods. The findings offer valuable insights into potential treatments for this condition, addressing a critical unmet medical need. Further research and clinical trials are warranted to validate the effectiveness of these repurposed drugs in preventing surgery related to intestinal fibrosis in CD patients.
Keyphrases
- end stage renal disease
- clinical trial
- ejection fraction
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- healthcare
- prognostic factors
- systematic review
- peritoneal dialysis
- coronary artery bypass
- risk assessment
- coronary artery disease
- machine learning
- big data
- percutaneous coronary intervention
- artificial intelligence
- open label
- surgical site infection