Presence of Liver Steatosis Is Associated With Greater Diabetes Remission After Gastric Bypass Surgery.
Pieter-Jan MartensRickesha L WilsonDeepa V CherlaChao TuSangeeta R KashyapDavid E CummingsPhilip R SchauerAli AminianPublished in: Diabetes care (2020)
This study, for the first time, suggests that in patients with T2DM who are considering bariatric and metabolic surgery, coexistence of liver steatosis is associated with better long-term glycemic outcomes. Furthermore, our data suggest that there are distinct variants of T2DM in which metabolic responses to surgical weight loss are different. A subgroup of patients whose T2DM is characterized by the presence of hepatic steatosis (presumably associated with worse IR) experience better postoperative metabolic outcomes.
Keyphrases
- weight loss
- gastric bypass
- glycemic control
- roux en y gastric bypass
- bariatric surgery
- type diabetes
- minimally invasive
- coronary artery bypass
- insulin resistance
- end stage renal disease
- obese patients
- chronic kidney disease
- high fat diet
- newly diagnosed
- ejection fraction
- gene expression
- patients undergoing
- copy number
- weight gain
- machine learning
- cardiovascular disease
- electronic health record
- patient reported outcomes
- rheumatoid arthritis
- high fat diet induced
- metabolic syndrome
- randomized controlled trial
- big data
- coronary artery disease