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Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.

Karim SallamDilip ThomasSadhana GaddamNicole LopezAimee BeckLeila BeachAlbert J RogersHao ZhangIan Ying-Li ChenMohamed AmeenWilliam HiesingerJeffrey J TeutebergJune-Wha RheeKevin C WangNazish SayedJoseph C Wu
Published in: Circulation (2022)
Keyphrases
  • single cell
  • rna seq
  • endothelial cells
  • induced pluripotent stem cells
  • high glucose
  • high throughput
  • drug induced
  • diabetic rats
  • left ventricular
  • pluripotent stem cells
  • oxidative stress
  • heart failure