Inflammation, coronary plaque progression, and statin use: A secondary analysis of the Risk Stratification with Image Guidance of HMG CoA Reductase Inhibitor Therapy (RIGHT) study.
Colin ScottSundus S LateefChristin G HongAmit K DeyGrigory A ManyakNidhi H PatelWunan ZhouAlexander V SorokinKhaled AbdelrahmanDomingo UcedaMeron TekluColin WuPhilip M ParelVeit SandfortMarcus Y ChenMarissa MallekMark AhlmanDavid A BluemkeNehal N MehtaPublished in: Clinical cardiology (2022)
Statin treatment over 2 years associated with a significant increase in coronary calcification in patients with higher systemic inflammation, as measured by hs-CRP. These findings suggest that systemic inflammation plays a role in coronary calcification and further studies should be performed to better elucidate these findings.
Keyphrases
- coronary artery disease
- coronary artery
- chronic kidney disease
- cardiovascular disease
- oxidative stress
- aortic stenosis
- deep learning
- stem cells
- type diabetes
- fatty acid
- heart failure
- mesenchymal stem cells
- combination therapy
- ejection fraction
- transcatheter aortic valve replacement
- machine learning
- low density lipoprotein
- replacement therapy