The effect of progestin therapy in advanced and recurrent endometrial cancer: A systematic review and meta-analysis.

Willem Jan van WeeldenPhiline B BirkendahlRoy I LalisangJoanna IntHoutRoy F P M KruitwagenAndrea RomanoJohanna M A Pijnenborg

Published in: BJOG : an international journal of obstetrics and gynaecology (2022)

Progestin therapy is a viable treatment option in patients with advanced stage and recurrent EC with low toxicity and high ORR in PR-positive disease. The role of PR expression in relation to progression-free survival and overall survival is unclear.

Keyphrases

free survival
endometrial cancer
poor prognosis
oxidative stress
stem cells
cell therapy
replacement therapy